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Promethazine
Clinical data
Trade namesMany [1]
AHFS/Drugs.comMonograph
MedlinePlusa682284
Pregnancy categoryAU: C US: C (Risk not ruled out)
Routes of administrationOral, rectal, IV, IM, topical
ATC codeD04AA10 ( WHO ) R06AD02 ( WHO )
Legal status
Legal statusAU: S3 (Pharmacist only) CA : OTC UK: P (Pharmacy medicines) (POM when injection), US: ℞-only South Africa: S5 IV S2 Oral
Pharmacokinetic data
Bioavailability88% absorbed but after first-pass metabolism reduced to 25% absolute bioavailability [2]
Protein binding93%
MetabolismHepatic glucuronidation and sulfoxidation
Elimination half-life16–19 hours [2] [3]
ExcretionRenal and biliary

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Thank you so much for your kind words. I really enjoy your blog as well since my first passion in life has always been books! 🙂

  • It’s easy to enjoy the simple pleasures in Italy.

    • e vero.. I very much believe in the concept of living life slowly (when I;m not working.. 😉

  • Hi!

    I have nominated your blog for the Adventurous Blogger Award! I would be very grateful if you accept. Thank you :D.

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  • What a great blog you have here! 🙂

  • GIRL! im so happy i came accross your blog. you look awesome and have lovely info! thanks for the follow back on twitter. we should kick it sometime!
    -danella (and scott, even though he didnt write this lol)

    • aww thank you for the kind words :-), compliments will get you everywhere haha 🙂

  • Hi Georgette, I just nominated you for the Very Inspiring Blogger Award! Congratulations!

    • Thank you! That meets a lot to me, grazie. Gracias, merci, danke!

  • sherry willome
    • Thank you Sherry for the kind words! 🙂

      • Sherry Willome

        Is your husband a tour guide???

  • Cathy New York
  • Georgette, your blog is amazing! You are totally killing it.
    My heart is so warmed knowing that you are making it in Florence. You were so important to helping me get through my time there.

    I’m doubly, no triply, impressed because I could never imagine working on my blog in Florence (well, on Via Isonzo).

    And congratulations to you and Tomasso on seven years together! I’m very happy for you both.

    baci,
    Melissa

    • I hear you! What’s it like starting a new life in America? I am always curious about how it is for those coming to live in the USA. 😀

  • Ever heard of the sweetness of doing nothing? :-). Italians mastered it! 😉 I’m partly Italian and proud of it

    • Ah yes! ‘Il Dolce far niente’ – I LOVE this about Italy, my kind of country indeed!

  • Please have a cone for me at festivale del gelato 🙂 you lucky girl

    • Hello Sean, thank you! If you send me an email via my contact form, I’ll get back to you asap!

  • Missy
    • Thank you for reading my blog! Ive certainly been there myself so I totally understand. Good luck to you!

      • Missy
  • Thank you for sharing!! We hope to make it to Florence someday 🙂

    kytril

  • Valeria
  • Lovely blog, Georgette! Thanks for connecting with us on Twitter! Keep up the great work and travel safe! Oh… and a happy New Year! 🙂

  • Hi, pleased to meet you! 🙂

    • nice to meet you too! I adore your blog, love to see all of the updated events. GREAT job

  • Kris
    • Ciao Jenifer, your comment made me blush 🙂 I hope I can continue to grab your interest.

    • hey, thanks for checking it out! I am sure you will be just fine, especially if you already live abroad 🙂 good luck with your journey!

      • Any chance you have some tips for finding apartments? Scams seem to run rampant! I’m doing my best to make sure I don’t get stiffed.

  • Anna Evans
    • that is so hard to say because it really depends on how much (and what you eat). I would say I spend around 50-70 euros a week on food

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    Thanks Georgette, sound like that’s about right then!
    I hope this application works…
    Anna

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  • Dave

    I can’t take my eyes off your beautiful face, wondering if you met a special man in Florence?
    I am confused on one thing: Is it Georgette or Sophia? You are ONE woman, correct? Dave

  • ALex

    Hello Georgette,
    do you know how and where to find a job in Florence?
    ALex from Wimbledon.

  • Stacey
    • Stacey

      OK, I am guessing you don’t reply any more to comments here… If you read this, thanks anyway. Your site is very informative!

  • Eric
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  • Katherine Lenzi
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  • Tullio Bertoli
    • Sure there is these guys diphenhydramine who specialize in the area and since you don’t live here full time, it would make sense to go with an agency. Good luck!

      • Tullio Bertoli

        Thank you very much.

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